A Comfort Food Mashup: Meatloaf Meets Mac & Cheese

This Mac and Cheese Meatloaf Casserole is a bold twist on two comfort classics. A hearty meatloaf layer is topped with creamy macaroni and cheddar, then smothered in a tangy ketchup-milk glaze and baked to golden perfection. It’s a one-dish wonder that’s guaranteed to please picky eaters and comfort food lovers alike!

Perfect for family dinners, meal prep, or when you want a taste of nostalgia with a twist.


Why You’ll Love This Recipe:

  • 🥩 Meatloaf Base: Savory, seasoned ground beef creates a rich foundation.
  • 🧀 Cheesy Mac Layer: Topped with tender macaroni and melted cheddar for that classic combo.
  • 🍅 Ketchup-Milk Glaze: A sweet-tangy sauce that caramelizes during baking—odd but oddly delicious!
  • ⏱️ Quick Assembly: No fancy tools needed—just mix, layer, and bake.
  • 🎉 Great for Sharing: Ideal at potlucks, school lunches, or weeknight dinners.

Ingredients (Serves 6–8):

For the Meatloaf Layer:

  • 1 lb ground beef (or ground turkey for lighter version)
  • 1 cup breadcrumbs (plain or seasoned – adds texture and binds meat)
  • 2 large eggs , beaten (binds everything together)
  • Salt and black pepper , to taste

For the Mac & Cheese Layer:

  • 1 cup cooked macaroni noodles (boiled and drained – al dente works best)
  • 1 cup shredded cheddar cheese (or mozzarella for extra stretch)

For the Topping:

  • 1 cup ketchup (for tangy-sweet glaze)
  • 1 cup milk (creates a rich, bubbly topping—yes, it works!)

Instructions:

Step 1: Preheat Oven & Prep Pan

Preheat oven to 375°F (190°C) .

Grease a 9×13-inch baking dish or oven-safe skillet to prevent sticking.

Set aside while mixing the layers.


Step 2: Mix the Meatloaf Base

In a large bowl:

  • Combine ground beef , breadcrumbs , beaten eggs , salt , and pepper .
  • Mix gently with your hands until just combined—avoid overmixing to keep it tender.

Press the meatloaf mixture firmly into the bottom of the prepared pan like a dense crust.


Step 3: Add the Mac & Cheese Layer

Spread the cooked macaroni noodles evenly over the meatloaf base.

Sprinkle cheddar cheese over the pasta for a gooey finish.


Step 4: Pour on the Ketchup-Milk Sauce

In a small bowl:

  • Mix ketchup and milk until smooth.
  • Pour the mixture over the mac and cheese layer, covering completely.

This creates a sticky, slightly sweet sauce that bakes into a caramelized topping—trust the process!


Step 5: Bake Until Golden & Juicy

Bake at 375°F (190°C) for 45 minutes , or until:

  • The meatloaf reaches 160°F internally
  • The mac and cheese is bubbly
  • The ketchup glaze is golden and slightly thickened

Let cool for 10 minutes before slicing—this helps everything set.


Step 6: Serve Warm & Hearty

Cut into generous squares and serve warm.

Each bite brings together:

  • Savory, seasoned meatloaf crust
  • Creamy, cheesy macaroni layer
  • And that sweet-tangy ketchup-milk finish

It’s like a hug from your childhood dinner table.


Tips for Success:

  • 🧈 Use Cold Hands: Helps shape and press the meatloaf layer without sticking.
  • 🧑‍🍳 Add Veggies: Stir in frozen peas or carrots with the macaroni for extra nutrition.
  • 🧀 Cheese Swap Magic: Try Gouda, Monterey Jack, or vegan cheese for different flavors.
  • 🍞 Bread Crumb Hack: Crush crackers or pretzels for a crunchy twist.
  • ❄️ Make Ahead Magic: Assemble and refrigerate overnight—bake fresh when ready.

Serving Suggestions:

  • Pair with green beans, roasted broccoli, or a crisp salad for balance.
  • Great with cornbread, garlic bread, or crusty rolls.
  • Ideal for school lunches, family dinners, or movie night snacks.

Nutritional Information (per serving, makes 6 servings – approximate):

(With regular cheese and beef – per square)

  • Calories: ~300 kcal
  • Protein: ~15g
  • Carbohydrates: ~20g
  • Fat: ~18g
  • Fiber: ~0.5g
  • Sugar: ~6g

This Mac and Cheese Meatloaf Casserole proves that comfort food can still surprise you. With its meaty base, cheesy middle, and sweet-ketchup glaze—it’s a must-bake for anyone who loves bold, nostalgic flavors.

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